Mediators of antiretroviral adherence: A multisite international study

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dc.contributor.authorCorless, Inge
dc.contributor.authorGuarino, Alessio
dc.contributor.authorNicholas, Patrice
dc.contributor.authorTyer-Viola, Lynda
dc.contributor.authorKirksey, Kenn
dc.contributor.authorBrion, John
dc.contributor.authorDawson Rose, Carol
dc.contributor.authorSanzero Eller, Lucille
dc.contributor.authorRivero-Mendez, Marta
dc.contributor.authorKemppainen, Jeanne
dc.contributor.authorNokes, Kathleen
dc.contributor.authorSefcik, Elizabeth
dc.contributor.authorVoss, Joachim
dc.contributor.authorWantland, dean
dc.contributor.authorJohnson, Mallory O.
dc.contributor.authorPhillips, J. Craig
dc.contributor.authorWebel, A.
dc.contributor.authorIipinge, Scholastika Ndatinda
dc.contributor.authorPortillo, Carmen
dc.contributor.authorChen, Wei-ti
dc.contributor.authorMaryland, M.
dc.contributor.authorHamilton, M.J.
dc.contributor.authorReid, P.
dc.contributor.authorHickey, D.
dc.contributor.authorHolzemer, William
dc.contributor.authorSullivan, K.
dc.contributor.authorCorless, Inge
dc.contributor.authorGuarino, Alessio
dc.contributor.authorNicholas, Patrice
dc.contributor.authorTyer-Viola, Lynda
dc.contributor.authorKirksey, Kenn
dc.contributor.authorBrion, John
dc.contributor.authorDawson Rose, Carol
dc.contributor.authorSanzero Eller, Lucille
dc.contributor.authorRivero-Mendez, Marta
dc.contributor.authorKemppainen, Jeanne
dc.contributor.authorNokes, Kathleen
dc.contributor.authorSefcik, Elizabeth
dc.contributor.authorVoss, Joachim
dc.contributor.authorWantland, dean
dc.contributor.authorJohnson, Mallory O.
dc.contributor.authorPhillips, J. Craig
dc.contributor.authorWebel, A.
dc.contributor.authorIipinge, Scholastika Ndatinda
dc.contributor.authorPortillo, Carmen
dc.contributor.authorChen, Wei-ti
dc.contributor.authorMaryland, M.
dc.contributor.authorHamilton, M.J.
dc.contributor.authorReid, P.
dc.contributor.authorHickey, D.
dc.contributor.authorHolzemer, William
dc.contributor.authorSullivan, K.
dc.creator.orcidhttps://orcid.org/0000-0003-0438-2037en_US
dc.creator.orcidhttps://orcid.org/0000-0001-9519-7587en_US
dc.creator.orcidhttps://orcid.org/0000-0002-8997-3671en_US
dc.creator.orcidhttps://orcid.org/0000-0002-4251-6801en_US
dc.creator.orcidhttps://orcid.org/0000-0002-4592-3525en_US
dc.creator.orcidhttps://orcid.org/0000-0001-6066-1853en_US
dc.creator.orcidhttps://orcid.org/0000-0003-1883-8509en_US
dc.creator.orcidhttps://orcid.org/0000-0001-8710-6139en_US
dc.creator.orcidhttps://orcid.org/0000-0003-4106-6498en_US
dc.creator.orcidhttps://orcid.org/0000-0001-9026-4189en_US
dc.creator.orcidhttps://orcid.org/0000-0002-3551-8016en_US
dc.creator.orcidhttps://orcid.org/0000-0002-8072-6244en_US
dc.creator.orcidhttps://orcid.org/0000-0002-4277-187Xen_US
dc.creator.orcidhttps://orcid.org/0000-0002-9785-6467en_US
dc.creator.orcidhttps://orcid.org/0000-0002-2741-7821en_US
dc.creator.orcidhttps://orcid.org/0000-0002-4400-9432en_US
dc.creator.orcidhttps://orcid.org/0000-0003-0438-2037
dc.creator.orcidhttps://orcid.org/0000-0001-9519-7587
dc.creator.orcidhttps://orcid.org/0000-0002-8997-3671
dc.creator.orcidhttps://orcid.org/0000-0002-4251-6801
dc.creator.orcidhttps://orcid.org/0000-0002-4592-3525
dc.creator.orcidhttps://orcid.org/0000-0001-6066-1853
dc.creator.orcidhttps://orcid.org/0000-0003-1883-8509
dc.creator.orcidhttps://orcid.org/0000-0001-8710-6139
dc.creator.orcidhttps://orcid.org/0000-0003-4106-6498
dc.creator.orcidhttps://orcid.org/0000-0001-9026-4189
dc.creator.orcidhttps://orcid.org/0000-0002-3551-8016
dc.creator.orcidhttps://orcid.org/0000-0002-8072-6244
dc.creator.orcidhttps://orcid.org/0000-0002-4277-187X
dc.creator.orcidhttps://orcid.org/0000-0002-9785-6467
dc.creator.orcidhttps://orcid.org/0000-0002-2741-7821
dc.creator.orcidhttps://orcid.org/0000-0002-4400-9432
dc.date.accessioned2022-03-30T15:34:35Z
dc.date.available2022-03-30T15:34:35Z
dc.date.issued2013-03
dc.date.issued2013-03
dc.description.abstractThe purpose of this study was to investigate the effects of stressful life events (SLE) on medication adherence (3 days, 30 days) as mediated by sense of coherence (SOC), self-compassion (SCS), and engagement with the healthcare provider (eHCP) and whether this differed by international site. Data were obtained from a cross-sectional sample of 2082 HIV positive adults between September 2009 and January 2011 from sites in Canada, China, Namibia, Puerto Rico, Thailand, and US. Statistical tests to explore the effects of stressful life events on antiretroviral medication adherence included descriptive statistics, multivariate analysis of variance, analysis of variance with Bonferroni post-hoc analysis, and path analysis. An examination by international site of the relationships between SLE, SCS, SOC, and eHCP with adherence (3 days and 30 days) indicated these combined variables were related to adherence whether 3 days or 30 days to different degrees at the various sites. SLE, SCS, SOC, and eHCP were significant predictors of adherence past 3 days for the United States (p = < 0.001), Canada (p = 0.006), and Namibia (p = 0.019). The combined independent variables were significant predictors of adherence past 30 days only in the United States and Canada. Engagement with the provider was a significant correlate for antiretroviral adherence in most, but not all, of these countries. Thus, the importance of eHCP cannot be overstated. Nonetheless, our findings need to be accompanied by the caveat that research on variables of interest, while enriched by a sample obtained from international sites, may not have the same relationships in each country.en_US
dc.identifier.citationCorless, I.B., Guarino, A.J., Nicholas, P.K., Tyer-Viola, L., Kirksey, K., Brion, J., Dawson Rose, C., Eller, L.S., Rivero-Mendez, M., Kemppainen, J. and Nokes, K., 2013. Mediators of antiretroviral adherence: a multisite international study. AIDS care, 25(3), pp.364-377.en_US
dc.identifier.doihttps://doi.org/10.1080/09540121.2012.701723
dc.identifier.doihttps://doi.org/10.1080/09540121.2012.701723
dc.identifier.urihttps://hdl.handle.net/1969.6/90342
dc.identifier.urihttps://hdl.handle.net/1969.6/90342
dc.language.isoen_USen_US
dc.publisherTaylor and Franics Onlineen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectadherenceen_US
dc.subjectstressful life eventsen_US
dc.subjectsense of coherenceen_US
dc.subjectself-compassionen_US
dc.subjectengagement with the provideren_US
dc.subjectHIV/AIDSen_US
dc.titleMediators of antiretroviral adherence: A multisite international studyen_US
dc.typeArticleen_US

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