Assessing embryonic toxicity and end fates of nanoplastics in freshwater environments using gastropod Biomphalaria Glabrata

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dc.contributor.advisorXu, Wei
dc.contributor.authorMerrill, MacKenzie Leigh
dc.contributor.committeeMemberBahr, Keisha
dc.contributor.committeeMemberWagner, Daniel
dc.contributor.committeeMemberMozzachiodi, Riccardo
dc.creator.orcidhttps://orcid.org/0000-0002-5495-3582en_US
dc.date.accessioned2022-12-06T20:52:33Z
dc.date.available2022-12-06T20:52:33Z
dc.date.issued2022-07-22
dc.descriptionA thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Biology from Texas A&M University-Corpus Christi in Corpus Christi, Texas.en_US
dc.description.abstractThe wide use of plastics has resulted in not only the accumulation of macroplastic pollution in the aquatic environment but also plastic particles at micro and nano levels (MPs and NPs). Accumulation of these MPs and NPs have numerous adverse effects on the morphology, behavior, and reproduction of living organisms. In this study, we investigated the effects of NPs on the embryonic development of Biomphalaria glabrata, a commonly used gastropod in toxicology studies. This study identified the adsorption of NPs by the embryos of B. glabrata and showed evidence of NP absorption by the hatched juveniles. NP bioaccumulation subsequently triggered the alteration in the expression of several stress response genes, including heat shock protein-70 (HSP70), cytochrome P450 (CYP450), and macrophage migration inhibitory factor (MIF). With the influence of NPs, the hatching rates of B. glabrata embryos varied depending on the sizes of NPs. In addition, the NPs with mean diameters of 1.0 µm or 0.03 µm led to higher embryo mortality rates than 0.5 µm NPs. This preliminary study demonstrated the impact of NPs on the development of B. glabrata embryos. Further studies on the mechanism of NP toxic effects are desired.en_US
dc.description.collegeCollege of Science and Engineeringen_US
dc.description.departmentLife Sciencesen_US
dc.format.extent52 pagesen_US
dc.identifier1969.6/1139
dc.identifier.urihttps://hdl.handle.net/1969.6/94539
dc.language.isoen_USen_US
dc.rightsThis material is made available for use in research, teaching, and private study, pursuant to U.S. Copyright law. The user assumes full responsibility for any use of the materials, including but not limited to, infringement of copyright and publication rights of reproduced materials. Any materials used should be fully credited with its source. All rights are reserved and retained regardless of current or future development or laws that may apply to fair use standards. Permission for publication of this material, in part or in full, must be secured with the author and/or publisher.
dc.rightsThis material is made available for use in research, teaching, and private study, pursuant to U.S. Copyright law. The user assumes full responsibility for any use of the materials, including but not limited to, infringement of copyright and publication rights of reproduced materials. Any materials used should be fully credited with its source. All rights are reserved and retained regardless of current or future development or laws that may apply to fair use standards. Permission for publication of this material, in part or in full, must be secured with the author and/or publisher.en_US
dc.subjectaquatic toxicologyen_US
dc.subjectbioaccumulationen_US
dc.subjectbiomphalariaen_US
dc.subjectecotoxicityen_US
dc.subjectnanoplasticen_US
dc.titleAssessing embryonic toxicity and end fates of nanoplastics in freshwater environments using gastropod Biomphalaria Glabrataen_US
dc.typeText
dc.typeTexten_US
dc.type.genreThesis
dc.type.genreThesisen_US
thesis.degree.disciplineBiologyen_US
thesis.degree.grantorTexas A & M University--Corpus Christi
thesis.degree.grantorTexas A & M University--Corpus Christien_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Scienceen_US

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