90-90-90-plus: Maintaining adherence to antiretroviral therapies

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dc.contributor.authorCorless, Inge
dc.contributor.authorHoyt, Alex
dc.contributor.authorTyer-Viola, Lynda
dc.contributor.authorSefcik, Elizabeth
dc.contributor.authorKemppainen, Jeanne
dc.contributor.authorHolzemer, William
dc.contributor.authorSanzero Eller, Lucille
dc.contributor.authorNokes, Kathleen
dc.contributor.authorPhillips, J. Craig
dc.contributor.authorDawson Rose, Carol
dc.contributor.authorRivero-Mendez, Marta
dc.contributor.authorIipinge, Scholastika Ndatinda
dc.contributor.authorChaiphibalsarisdi, Puangtip
dc.contributor.authorPortillo, Carmen J.
dc.contributor.authorChen, Wei-Ti
dc.contributor.authorWebel, Allison
dc.contributor.authorBrion, John
dc.contributor.authorJohnson, Mallory O.
dc.contributor.authorVoss, Joachim
dc.contributor.authorHamilton, Mary Jane
dc.contributor.authorSullivan, Kathleen M.
dc.contributor.authorKirksey, Kenn
dc.contributor.authorNicholas, Patrice
dc.contributor.authorCorless, Inge
dc.contributor.authorHoyt, Alex
dc.contributor.authorTyer-Viola, Lynda
dc.contributor.authorSefcik, Elizabeth
dc.contributor.authorKemppainen, Jeanne
dc.contributor.authorHolzemer, William
dc.contributor.authorSanzero Eller, Lucille
dc.contributor.authorNokes, Kathleen
dc.contributor.authorPhillips, J. Craig
dc.contributor.authorDawson Rose, Carol
dc.contributor.authorRivero-Mendez, Marta
dc.contributor.authorIipinge, Scholastika Ndatinda
dc.contributor.authorChaiphibalsarisdi, Puangtip
dc.contributor.authorPortillo, Carmen J.
dc.contributor.authorChen, Wei-Ti
dc.contributor.authorWebel, Allison
dc.contributor.authorBrion, John
dc.contributor.authorJohnson, Mallory O.
dc.contributor.authorVoss, Joachim
dc.contributor.authorHamilton, Mary Jane
dc.contributor.authorSullivan, Kathleen M.
dc.contributor.authorKirksey, Kenn
dc.contributor.authorNicholas, Patrice
dc.creator.orcidhttps://orcid.org/0000-0003-0438-2037en_US
dc.creator.orcidhttps://orcid.org/0000-0003-0334-8937en_US
dc.creator.orcidhttps://orcid.org/0000-0002-8997-3671en_US
dc.creator.orcidhttps://orcid.org/0000-0002-3551-8016en_US
dc.creator.orcidhttps://orcid.org/0000-0003-4106-6498en_US
dc.creator.orcidhttps://orcid.org/0000-0002-4400-9432en_US
dc.creator.orcidhttps://orcid.org/0000-0003-1883-8509en_US
dc.creator.orcidhttps://orcid.org/0000-0001-9026-4189en_US
dc.creator.orcidhttps://orcid.org/0000-0001-6066-1853en_US
dc.creator.orcidhttps://orcid.org/0000-0001-8710-6139en_US
dc.creator.orcidhttps://orcid.org/0000-0002-9785-6467en_US
dc.creator.orcidhttps://orcid.org/0000-0002-5744-6279en_US
dc.creator.orcidhttps://orcid.org/0000-0002-7538-5780en_US
dc.creator.orcidhttps://orcid.org/0000-0002-4592-3525en_US
dc.creator.orcidhttps://orcid.org/0000-0002-8072-6244en_US
dc.creator.orcidhttps://orcid.org/0000-0002-4251-6801en_US
dc.creator.orcidhttps://orcid.org/0000-0001-9519-7587en_US
dc.creator.orcidhttps://orcid.org/0000-0003-0438-2037
dc.creator.orcidhttps://orcid.org/0000-0003-0334-8937
dc.creator.orcidhttps://orcid.org/0000-0002-8997-3671
dc.creator.orcidhttps://orcid.org/0000-0002-3551-8016
dc.creator.orcidhttps://orcid.org/0000-0003-4106-6498
dc.creator.orcidhttps://orcid.org/0000-0002-4400-9432
dc.creator.orcidhttps://orcid.org/0000-0003-1883-8509
dc.creator.orcidhttps://orcid.org/0000-0001-9026-4189
dc.creator.orcidhttps://orcid.org/0000-0001-6066-1853
dc.creator.orcidhttps://orcid.org/0000-0001-8710-6139
dc.creator.orcidhttps://orcid.org/0000-0002-9785-6467
dc.creator.orcidhttps://orcid.org/0000-0002-5744-6279
dc.creator.orcidhttps://orcid.org/0000-0002-7538-5780
dc.creator.orcidhttps://orcid.org/0000-0002-4592-3525
dc.creator.orcidhttps://orcid.org/0000-0002-8072-6244
dc.creator.orcidhttps://orcid.org/0000-0002-4251-6801
dc.creator.orcidhttps://orcid.org/0000-0001-9519-7587
dc.date.accessioned2022-03-30T15:08:35Z
dc.date.available2022-03-30T15:08:35Z
dc.date.issued2017-05-01
dc.date.issued2017-05-01
dc.description.abstractMedication adherence is the “Plus” in the global challenge to have 90% of HIV-infected individuals tested, 90% of those who are HIV positive treated, and 90% of those treated achieve an undetectable viral load. The latter indicates viral suppression, the goal for clinicians treating people living with HIV (PLWH). The comparative importance of different psychosocial scales in predicting the level of antiretroviral adherence, however, has been little studied. Using data from a cross-sectional study of medication adherence with an international convenience sample of 1811 PLWH, we categorized respondent medication adherence as None (0%), Low (1–60%), Moderate (61–94%), and High (95–100%) adherence based on self-report. The survey contained 13 psychosocial scales/indices, all of which were correlated with one another (p < 0.05 or less) and had differing degrees of association with the levels of adherence. Controlling for the influence of race, gender, education, and ability to pay for care, all scales/indices were associated with adherence, with the exception of Berger's perceived stigma scale. Using forward selection stepwise regression, we found that adherence self-efficacy, depression, stressful life events, and perceived stigma were significant predictors of medication adherence. Among the demographic variables entered into the model, nonwhite race was associated with double the odds of being in the None rather than in the High adherence category, suggesting these individuals may require additional support. In addition, asking about self-efficacy, depression, stigma, and stressful life events also will be beneficial in identifying patients requiring greater adherence support. This support is essential to medication adherence, the Plus to 90-90-90.en_US
dc.description.sponsorshipThis project was supported, in part, by NIH UL1 RR024131; NIH T32NR007081; NIH KL2RR024990; NIH R15NR011130; International Pilot Award, University of Washington Center for AIDS Research; University of British Columbia School of Nursing Helen Shore Fund; Duke University School of Nursing Office of Research Affairs; MGH Institute for Health Professions; Rutgers College of Nursing; City University of New York; Texas A&M University-Corpus Christi College of Nursing and Health Sciences; University of North Carolina-Wilmington-Irwin Belk distinguished professor of nursing funding.en_US
dc.identifier.citationCorless, I.B., Hoyt, A.J., Tyer-Viola, L., Sefcik, E., Kemppainen, J., Holzemer, W.L., Eller, L.S., Nokes, K., Phillips, J.C., Dawson-Rose, C. and Rivero-Mendez, M., 2017. 90-90-90-Plus: Maintaining adherence to antiretroviral therapies. AIDS patient care and STDs, 31(5), pp.227-236.en_US
dc.identifier.doihttps://doi.org/10.1089/apc.2017.0009
dc.identifier.doihttps://doi.org/10.1089/apc.2017.0009
dc.identifier.urihttps://hdl.handle.net/1969.6/90338
dc.identifier.urihttps://hdl.handle.net/1969.6/90338
dc.language.isoen_USen_US
dc.publisherMary Ann Lieberten_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectadherenceen_US
dc.subject90-90-90en_US
dc.subjectARTen_US
dc.subjectpredictorsen_US
dc.title90-90-90-plus: Maintaining adherence to antiretroviral therapiesen_US
dc.typeArticleen_US

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